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Bio X Cell

Located in New Hampshire, USA, Bio X Cell is a trusted supplier of ultra-pure, low endotoxin antibodies that are formulated without preservatives or stabilisers. Targeting both highly characterised and novel antigens, including many well-known immune checkpoints and various proteins implicated in cancer, these are available in the large quantities required for in vivo pre-clinical studies.

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Bio X Cell

The Gold Standard For In Vivo Monoclonal Antibodies

  • Products with unparalleled quality manufactured in the U.S. Our industry-leading InVivoMAb and InVivoPlus antibodies are all manufactured in our own facility in the U.S. and never outsourced from another manufacturer.
  • Extensive library of product citations in peer-reviewed publications. These publications not only provide an unbiased source of antibody validation but also an invaluable source of protocol details for in vivo experiments to help accelerate research findings.
  • Expert technical support and customer service. Our dedicated support team includes PhD scientists with extensive pre-clinical research experience, who strive to provide well thought out answers to your questions with lightning speed.
  • Best in industry value and instant product availability. You can count on us to have the critical reagents you need in stock at the moment you need them.
  • An ever-growing selection of functionally active, blocking, neutralizing and agonistic antibodies. These products cover a wide range of research areas including cancer, immunology, and more.
  • The Bio X Cell One-Year Shelf-Life Guarantee. We stand by the quality of our products and offer a one-year shelf-life guarantee. In the rare event that an antibody does not perform as indicated on the datasheet, we will provide a replacement or credit without hesitation.
  • Matching Isotype Control Antibodies Bio X Cell carries a wide selection of non-binding isotype control antibodies. This takes the guesswork out of finding the correct control for your antibody.

Bio X Cell Products Feature

  • Exceptional Purity Our optimized proprietary antibody manufacturing method ensures an ultra-pure antibody solution without added proteins or chemicals. Each lot is QC tested for purity using SDS-PAGE.
  • Ultra-low Endotoxin Levels The level of endotoxin is QC tested for each lot. Our InVivoMAb products are at or below 2EU/mg and InVivoPlus products are at or below 1EU/mg. If endotoxin levels below 1EU/mg are required, please simply contact our technical support for details.
  • Pathogen Free Each lot of InVivoPlus product is screened for an exhaustive panel of murine pathogens. The results are detailed on product-specific datasheets, to help you adhere to IACUC and Animal Facility requirements
  • Advanced Binding Validation We utilize a library of recombinant proteins and our bioassay expertise to validate that each lot of applicable InVivoPlus antibody binds strongly and specifically to its target antigen.

Contract Production Of Antibodies

Bio X Cell also provides production and purification services of antibodies produced from pre-existing hybridoma cell lines. These hybridomas are typically developed in the client’s laboratory or available in the public domain.

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Bio X Cell RecombiMAb™ Recombinant Antibodies

RecombiMAb™ antibodies are recombinant monoclonal antibodies with the identical antigen binding variable domains as the traditional clones that they are derived from, but the IgG constant regions have been switched from rat or hamster IgG to mouse or human IgG.

Bio X Cell RecombiMAb™ Recombinant Antibodies

Discover the InVivoPlus™ Difference

The shortest path between receiving your antibody and analyzing your results.

InVivoSIM™: Research-Grade Biosimilar Antibodies

Non-therapeutic antibodies are research-grade biosimilar monoclonal antibodies that have the same active biological component as the original therapeutic antibodies.