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Rockland Inc

Rockland Immunochemicals, Inc. offers each academic, biopharma, and diagnostic professional thousands of antibodies with the aim of providing the right antibody that is the perfect fit for every occasion. No matter the context – basic research to disease therapy, phosphorylated to methylated and beyond – Rockland embraces the challenge to design, produce, validate, and deliver the absolute best antibodies and life science reagents available in the market today and every day. With Rockland, your solution is complete.

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Rockland Inc

Patient Derived Tumor Models

Tumor modelling facilitates the study of tumor growth in the tumor microenvironment. Therapies that affect the tumor microenvironment are critical for advancing the fight against cancer as emerging therapies target the network of signaling pathways essential for tumor growth and metastasis. Patient derived tumor models, including melanoma cell lines and tumor xenografts, are invaluable tools to study normal and malignant cells, tumor formation and drug resistance. 

A diverse panel of melanoma cell lines, now available from Rockland Immunochemicals, is required to account for the varied genetic signatures of tumors, especially if the scientific goal is to establish drug sensitivity for tumor inhibition, therapy resistance, or tumor dormancy. Tumor xenografts are available from Rockland produced on a custom basis in murine models

Patient Derived Tumor Models

Reagents & Controls

Blocking reagents are essential to improving assay sensitivity by reducing background interference and increasing signal-to-noise ratios. Rockland manufactures high-quality blood products, including serum & plasma. Purified gamma globulin fractions can be used as blocking reagents as well as quantification standards and assay loading controls.

Reagents & Controls
Catalog No.
Goat Serum
Mouse Serum
Goat Gamma Globulin
Rabbit Gamma Globulin
Rabbit Anti-Human Serum Albumin Antibody
Rabbit Anti-Human RBC Antibody
Rabbit Anti-Sheep RBC Antibody
Red Blood Cell Depletion Magnetic Beads
Guinea Pig Complement (Fresh Frozen)

All of Rockland’s raw materials are produced in the United States at a USDA-regulated facility following fully traceable manufacturing processes and quality assurance systems. Control over the supply chain allows Rockland to maintain quality and consistency between lots and in-bulk production batch sizes.

Solutions, Stabilisers, & Substrates

Rockland offers supporting reagents to facilitate various immunoassays. Solutions, buffers, and stabilisers help maintain physiological conditions and promote protein-protein interactions. Substrates for reporter enzymes commonly used in immunoassays can produce soluble-colored or insoluble-colored products.

Solutions, Stabilizers, & SubstratesCatalog No.
10X PBS Fish gel (NaN3 & Hg free)MB-066-1000
BSA - Fraction VBSA-1000
BlockOut™ Universal Blocking BufferMB-073
ELISA Microwell Blocking BufferMB-064-1000
10X Phosphate-Buffered Saline (PBS)MB-008
10X Tris-Buffered Saline (TBS)MB-012
HRP Conjugate Stabilizer (NaN3 & Hg Free)MB-060-1000
3, 3’, 5, 5’-Tetramethylbenzidine ELISA (TMBE)TMBE-1000
3, 3’, 5, 5’-Tetramethylbenzidine Membrane (TMBM)TMBM-1000
BCIP/NBT Alkaline Phosphatase SubstrateNBT-100

Reporter molecules & Conjugates

Secondary antibodies and Protein A/G conjugates are common and economical methods for detecting and visualizing the antigen-primary antibody complex. The streptavidin-biotin system is an alternative to secondary antibodies and provides significant signal amplification for conjugated primary antibodies. Rockland’s strong manufacturing experience allows for bulk production of highly purified reporter molecules and their conjugates, reducing concerns of lot-to-lot consistency.

Reporter Molecules & ConjugatesCatalog No.
Goat Anti-Human IgG (H&L) Pre-adsorbed609-101-123
Rabbit Anti-Human IgM (Fc5µ)609-4131
Goat Anti-Mouse IgG (H&L) Pre-adsorbed610-101-121
Goat Anti-Rabbit IgG (H&L) Pre-adsorbed611-101-122
Donkey Anti-Goat (H&L) Pre-adsorbed605-701-125
Streptavidin Peroxidase ConjugatedS000-03
Protein APA00-00