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Cosmo Bio Ltd

Established in 1983, Cosmo Bio is a Japanese company that distributes its own research reagents, and the products of trusted Japanese partners, to support life science research worldwide. With a portfolio comprising over 5000 export quality antibodies, proteins, ELISA kits, cell biology and molecular biology reagents, as well as general consumables, Cosmo Bio serves a wide range of customer requirements.
Cosmo Bio’s mouse IVF products are especially of interest to our customers. Using Cosmo Bio’s ultra-superovulation reagent, CARD HyperOva, in combination with CARD FERTIUP® preincubation medium, CARD medium, and CARD mHTF, all of which are recommended by the Centre of Animal Resources and Development (CARD), researchers can perform murine in vitro fertilisation to successfully achieve 2-cell to blastocyst stage embryos via a relatively straightforward protocol.

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Researchers also turn to us for Cosmo Bio’s transfection reagents. We notice a lot of attention focused on Cosmo Bio’s GenomONE-Neo™, a unique product for transfection of nucleic acids, proteins, and small molecules. This delivers extremely efficient gene expression by utilising the high membrane fusion potential of inactivated Sendai virus particle (hemagglutinating virus of Japan envelope, HVJ-E). Unlike conventional non-virus transfection tools, HVJ-E has the capacity to resist degradation by lysosomes. Cosmo Bio’s cell fusion reagent, GenomONE™-CF EX, is another of our more popular products.

Also based on HVJ-E, this can be used with both adherent and suspension cells to achieve fusion in just 30 minutes. In combination with hybridoma growth supplement, GenomONE™-CF EX demonstrates a 100% antibody-production positive rate as compared to just 9% with PEG1500 under identical conditions, making it a superior alternative to traditional PEG-based methods of cell fusion.

CARD HyperOva®

Find out more about the Enhanced Superovulation Reagent for Mice from Cosmo Bio!

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CARD-HyperOva-pathway

Featured Products

F1-X™ Next-Gen Gibson Assembly®

The original Gibson assembly changed molecular cloning, enabling seamless, sequence-independent and simple construction of constructs.

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Purefrex 2.1

The purest of the the PURE-based reconstituted protein synthesis system kits with redox environment control.

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PURESYSTEM

Everything you need for PURE-based protein synthesis.

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CloverDirect™

Non-natural amino acid-charged tRNAs for site directed protein functionalisation.

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CD44 Antibodies and Kits

Explore Cosmo Bio's CD44 kits and antibodies for isolating cancer stem cells.

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Other IVF Products

In addition to the world's most trusted mouse IVF-related reagents from CARD/Kyudo, Cosmo Bio offer their own brand of high performance IVF-related reagents with a focus on value and convenience.

  • In addition to the world's most trusted mouse IVF-related reagents from CARD/Kyudo, Cosmo Bio offers our own brand of high performance IVF-related reagents of with a focus on value and convenience.  We offer an assortment of Cosmo Bio brand reagents for both mouse and rat in sizes that may be more compatible with your workflow.

    Quality and consistency are assured. Cosmo Bio brand reagents are produced and packaged in Japan under ISO9001 global quality management standards. All reagents are sealed in glass ampoules and store at 4°C with shelf lives of at least one year from the date of manufacture.

    Porcine IVF Product Name Size Cat. No.
    Basic Culture Kit for Porcine IVF Embryo Production 1 kit CSR-CK029
    Complete Culture Kit Porcine IVF Embryo Production 1 kit CSR-CK030
    POE-CM (Porcine Oocyte/Embryo Collection Medium) 5 x 100ml CSR-CK020
    POM (Basic Medium For Porcine Oocyte Maturation) 3 x 25ml CSR-CK021
    HP-POM (High Performance Porcine Oocyte Maturation Medium) 3 x 25ml CSR-CK022
    dbcAMP-100X (dbcAMP Concentrate, 100x Solution) 500ul CSR-CK027
    SEM-5X (Porcine Semen Dilution Medium) 25ml CSR-CK026
    PFM (Porcine Fertilization Medium) 2 x 100ml CSR-CK023
    PZM-5 (Porcine Embryo Development Medium) 3 x 25ml CSR-CK024
    PBM (Porcine Blastocyst Medium) 2 x 25ml CSR-CK025

  • See our list of IVF reagents offered by Cosmo Bio Ltd under our CSR reagent brand program.

    Porcine IVF Product Name Size Cat. No.
    Basic Culture Kit for Porcine IVF Embryo Production 1 kit CSR-CK029
    Complete Culture Kit Porcine IVF Embryo Production 1 kit CSR-CK030
    POE-CM (Porcine Oocyte/Embryo Collection Medium) 5 x 100ml CSR-CK020
    POM (Basic Medium For Porcine Oocyte Maturation) 3 x 25ml CSR-CK021
    HP-POM (High Performance Porcine Oocyte Maturation Medium) 3 x 25ml CSR-CK022
    dbcAMP-100X (dbcAMP Concentrate, 100x Solution) 500ul CSR-CK027
    SEM-5X (Porcine Semen Dilution Medium) 25ml CSR-CK026
    PFM (Porcine Fertilization Medium): CSR-CK023 2 x 100ml CSR-CK023
    PZM-5 (Porcine Embryo Development Medium) 3 x 25ml CSR-CK024
    PBM (Porcine Blastocyst Medium) 2 x 25ml CSR-CK025

  • In addition to the world's most trusted mouse IVF-related reagents from CARD/Kyudo, Cosmo Bio offers their own brand of high performance IVF-related reagents of with a focus on value and convenience.  They offer an assortment of Cosmo Bio brand reagents for both mouse and rat in sizes that may be more compatible with your workflow.

    Quality and consistency are assured. Cosmo Bio brand reagents are produced and packaged in Japan under ISO9001 global quality management standards. All reagents are sealed in glass ampoules and stored at 4°C with shelf lives of at least one year from the date of manufacture.

    Product Name and Composition Workflow Available Sizes Cat. No
    M2

    Composition: NaCl, KCl, KH2PO4, MgSO4.7H2O,
    Na-Lactate, Na-Pyruvate, Glucose, NaHCO3,
    CaCl2.2H2O, Penicillin, Streptomycin, Phenol Red,
    HEPES, BSA    		 Rat or Mouse Embryo
    in Manipulation    		 10 x 2ml
    10 x 5ml    		 CSR-R-M083
    CSR-R-M084
    PB1

    Composition: NaCl, KCl, KH2PO4, MgCl2.6H2O,
    Na2HPO4, Na-Pyruvate, Glucose, Penicillin,
    Streptomycin, BSA, H2O for Embryo Transfer (1ml)    		 Rat or Mouse Embryo
    Manipulation    		 10 x 2ml
    10 x 5ml    		 CSR-R-P185
    CSR-R-P138
    HTF (Human Tubal Fluid)

    Composition: NaCl, KCl, MgSO4.7H2O, KH2PO4,
    CaCl2, NaHCO3, Glucose, Na-Lactate, Na-Pyruvate,
    Penicillin G, Streptomycin, BSA.    		 Rat or Mouse In Vitro
    Fertilisation    		 10 x 2ml
    10 x 5ml    		 CSR-R-B070
    CSR-R-B071
    MR1ECM

    Composition: NaCl, KCl, CaCl2, MgCl2, NaHCO3,
    Na-Lactate, Na-Pyruvate, Glucose, PVA,
    L-Glutamine, Essential AA, Non Essential AA    		 Rat Embryo, In Vitro
    Development and
    Maturation    		 10 x 2ml
    10 x 5ml    		 CSR-R-M191
    CSR-R-M174
    Rat KSOM

    Composition: NaCl, KCl, MgSO4.7H2O, Na-Lactate,
    Glucose, Na-Pyruvate, NaHCO3, CaCl2, 100mM
    EDTA, L-Glutamine, Taurine, Glycine, Glutamate,
    Alanine, Penicillin G, Essential AA, Non Essential AA,
    BSA    		 Rat Embryo In Vitro
    Development and
    Maturation    		 10 x 1ml CSR-R-R148
    SPB1 Rat Embryo Thawing 10 x 2ml
    10 x 5ml    		 CSR-R-P185
    CSR-R-P138
    PEPes

    Composition: NaCl, KCl, CaCl2, KH2PO4,
    MgCl2.6H2O, Na-Pyruvate, Glucose, Penicillin,
    Steptomycin, BSA, Sucrose, Propanediol, Ethylene
    Glycol, Percoll.    		 Rat Embryo
    Vitrification    		 10 x 1ml CSR-R-P187

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At 2BScientific, we follow the motto “No-one does more for the customer” and we look forward to proving that to our valued customers!

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