Custom Targeted NGS Services

Services we offer

Delivering  high-quality, customised solutions for next-generation sequencing  by using targeted enrichment technology. Whether you require custom-designed probes, targeted sequencing solutions for niche genetic regions or complex DNA or RNA samples, including methylation sequencing with any downstream sequencing platform, including Illumina®, PacBio®, and Oxford Nanopore. 2BScientific ensures support to meet your specific research needs.

• The targeted sequencing uses myBaits capture probes that can be customised as per the target length . Using biotinylated baits, they provide high specificity and sensitivity for novel variant discovery (SNPs, indels, CNVs, etc.), and capture molecules of any length. The kits integrate easily with Library Prep Kits, detecting rare targets with minimal bias and preserving relative abundance signals. Supporting a wide range of targets, from single loci to large genomes.
• myReads services includes library preparation, hybridisation capture, sequencing, and bioinformatics analysis procedures, allowing us to tackle projects of any size successfully, even if  you have ancient/degraded DNA, standard DNA/RNA or long DNA inserts.
• Also Offers pre-designed custom kits with complete packages for Ultra Conserved Elements or Angiosperms-353; 16S-Hyb; Wheat exome and/or promoters; Respiratory viruses – dsDNA, ssDNA, RNA, or DNA + RNA, pre-designed community panels for fungi, animal, plants and forensic that has been used by previous researchers and optimised/validated for genome sequencing.

Key Benefits to the Customer 

• The unique capability of targeted enrichment is that it can generate high quality genetic data from diverse, rare, or challenging samples in a cost-effective manner without having to sequence the whole genome which has  supported researchers studying phylogenetics, population genetics, ecology, and plant research.
• Transparent communication throughout the project lifecycle.
• Flexibility of selecting your targets, the large capacity of sequence target range and clarity from the experts in the field from producing the library prep to decoding the data from their bioinformatics services.
• 1 to 1 discussion with the technical team or the 2BScientific Technical Product Managers for quotes, or the step-by-step process, on the kits and myReads services.

What the Process involves 

• Customers will first fill up the custom myBaits or myReads form (BELOW)
• Technical Product Managers will setup a call or send an email to understand the scope of the project, specific project requirements and the outcome customers require.
• Technical Product Managers can also arrange a Teams call with the technical team for further project understanding and customisation.