Triple Point Biologics
Triple Point Biologics began in 1994 to provide reagents to study the Matrix Metalloproteinases (MMPs) and their endogenous inhibitors (TIMPs). We produce antibodies and purified proteins for the research community to explore the role of MMPs and TIMPs in the wide range of normal and pathological conditions found in nature.
View All Triple Point Biologics Products
Since its founding in 1994, Triple Point Biologics has been a pioneering provider of high-quality reagents for the study of matrix metalloproteinases (MMPs) and their endogenous inhibitors (TIMPs). Dedicated to advancing research, the company produces antibodies and purified proteins that help uncover the intricate roles of MMPs and TIMPs in both normal and pathological conditions.
Triple Point Biologics was the first to introduce several key reagents to the research community and continues to be a trusted resource for cutting-edge MMP and TIMP products. As the family of proteolytic enzymes and inhibitors evolves, the company remains committed to meeting the growing needs of researchers worldwide.
Leading Products
Triple Point Biologics specializes in:
- Matrix Metalloproteinases (MMPs): Multifunctional proteases essential for physiological and pathological processes such as extracellular matrix breakdown, chemokine processing, and protease modulation.
- Tissue Inhibitors of Metalloproteinases (TIMPs): Endogenous regulators of ECM turnover and tissue remodelling, with four human TIMPs sharing significant sequence similarity.
- ADAMs and ADAMTS Enzymes: Members of the metzincin superfamily involved in critical cellular activities.
Research Focus
Key areas of focus include:
- MMP and TIMP Overexpression: Associated with diseases like cancer, atherosclerosis, and rheumatoid arthritis.
- Clinical Applications: Utilizing MMP/TIMP ratios and serum markers to diagnose and monitor diseases.
- Molecular Mechanisms in Disease: Investigating protein interactions to uncover cellular processes and disease pathways.
Future Innovations
To stay ahead of market needs, Triple Point Biologics is expanding its offerings:
- Recombinant antibodies
- Conjugated antibodies (biotin, HRP, fluorescent)
- Antibody and ELISA test kits
By combining innovation with a commitment to quality, Triple Point Biologics aims to remain a cornerstone of research in proteolytic enzymes and inhibitors.