Custom Knock in/Knock out Cell Services

Transcription factor-dependent reporter cell lines can be ideal tools for high-throughput RNAi, peptide, and chemical library screens. Responsive reporter cells form the core of cell-based assays for screening and identifying drugs, antibodies, cell factors, and other effectors. We can offer engineered stable reporter lines for almost any application–regardless of cell type.  

Engineered cell lines can be used to replicate specific mutations, either introducing/ knocking in or knocking out / knock down cell functions. Although many labs can use CRISPR mediated engineering to achieve the same function, using a service provider for knock ins or knock out cells can save time and resources in a laboratory, especially when the cell line also needs to be stable. Use our experts to allow your lab to concentrate on getting the results you need.  

2BScientific offers services for your cell line needs, with the provision of validated cell pools or clonal cell lines, checking for specific indels or insertions in alleles and potential wild type alleles that may otherwise affect results.  

Each project is designed to your specifications, so projects start with a call to assess and run through your requirements. We will assess your project and will offer a no obligation quote once you’re happy with the scope.