Bcell Design
Bcell Design’s platform is based on patented genetically modified mouse models secreting human chimeric antibodies.
Through this platform, IVD developers and manufacturers gain access to a wide range of monoclonal antibodies that are immediately ready for testing in human models.
2BScientific introduces Bcell Design, a supplier of monoclonal antibodies with a cutting-edge production technology. Their unique expertise sets them apart from the competition, allowing them to deliver human Fc monoclonal antibodies with exceptional reactivity, specificity, and stability. Quality assurance is at the core of our Bcell Design’s reagents, this is demonstrated by the way materials are purified through industrial in vitro cell culture processes, and each product undergoes rigorous quality controls, supported by Certificates of Analysis (CoA). They additionally achieved ISO9001 certification in 2024, further demonstrating their commitment to quality.
Uncompromising Commitment to Excellence
Bcell Design’s product offerings extend beyond the ordinary, providing a superior alternative to disease-state plasma. Additionally, they offer IgM, IgG, and IgA antibodies, each meticulously checked for sensitivity, specificity, and stability. Renowned manufacturers trust their monoclonal antibodies for use as positive controls, ensuring the reliability of their diagnostic applications. Services range from custom development to analytical characterisation, ensuring that our antibodies are tailored to the valued customers specific requirements.
Innovative Technology Platform
They additionally utilise a unique and patented platform built upon 15 years of expertise. Bcell Design’s genetically modified mouse models secrete human chimeric antibodies, offering IVD developers and manufacturers immediate access to a wide range of monoclonal antibodies ready for testing in human models. This platform maintains a single human isotype per mouse line, along with human Fc and the rest of their impressive immune catalogue.
Product Portfolio
Their antibodies have proven invaluable serve as an efficient and robust alternative to disease-state plasma. Additionally, IgA anti-CEA, has been instrumental in therapeutic development, particularly in mucosal cancer, secretory IgA, and oral immunotherapy. For those engaged in drug development, their monoclonal antibodies offer a powerful platform with a focus on safety, specificity, and therapeutic efficacy. Trust in Bcell Design to be your partner in advancing scientific and medical frontiers with cutting-edge monoclonal antibodies.
Characterised disease state plasma
The earlier a disease can be detected, the sooner therapy can start. In an infection, the earliest immune response is IgM, but it also tails off as IgG antibodies take up the challenge.
IgM detection would offer the earliest indication of disease, however creating diagnostic devices for IgM is challenging due to lack of control material, since the high levels of IgM decline relatively quickly, offering only a short window to identify potential donors for disease state plasma. Individual responses can vary and the levels of IgM in each sample needs to be characterized before use, which is time consuming, costly, and also uses up valuable sample.
B Cell Design offer monoclonal antibodies with Human Fc as the best alternative to characterised disease state plasma. These antibodies can be used to develop IVD tests such as ELISA and lateral flow, and are available to match your research schedule’s needs.
This solution offers consistent raw materials for immunoassay controls for industrial batch -to-batch reproducibility, or research needs. With consistent signal generation across batches, the human Fc mabs can be used to check antigen absorption and assay performance reducing the need for re-validations of control materials saving time & money!
Their range covers IgM, IgG, IgA and IgE, for a number of infectious agents, allergens and autoimmune antigens but they also offer custom manufacture if you can’t find what you’re looking for off the shelf!