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Lampire Biological Laboratories

Welcome to LAMPIRE Biological Laboratories, a pioneering biotech life science firm specializing in the creation and supply of vital biological reagents for the diagnostic and pharmaceutical industries. Their extensive offerings encompass tailor-made polyclonal and monoclonal antibody development, secondary antibodies, IgGs, BSA, animal blood, tissues, and organs. They also provide both normal and disease-state human serums and plasmas, along with cutting-edge cell media, OMNI C3 cell culture bags, contract manufacturing solutions, and an array of technical support services.

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Lampire Biological Laboratories

Novel Approach To Monoclonal Antibody Generation

Bovine Ultra-Long CDR3 Picobodies

Discover LAMPIRE’s monoclonal Bovine ultra-long CDR3 picobodies—compact, stable binding domains (3–5 kDa) derived from bovines. Using Single B-cell Sorting and Directed Sequencing, these antibodies advance targeted therapy development. In early preclinical stages, picobody-derived recombinant antibodies, including “knobbodies” and bispecific formats, show promise in binding viral and cancer epitopes. Unlock new possibilities in precision medicine with LAMPIRE’s Bovine B-cell technology.

Llama Monoclonal VHH Nanobodies

Accelerate monoclonal antibody discovery with LAMPIRE’s Llama B-cell approach. Our proprietary Single Cell Sorting of target-positive Llama and Alpaca B cells enables rapid, cost-effective VHH binder identification, with sequences recovered in just three weeks. By eliminating phage or yeast library costs and duplicate clone screening, our method maximizes efficiency. Capture the full antibody repertoire to explore clonotype relationships by affinity and epitope. Streamline developability assessments with in silico analysis, and enhance output with optional sequence refinement and humanization.

Rabbit Monoclonals

LAMPIRE offers rabbit monoclonal antibodies with high specificity, minimal off-target effects, and broad antigen detection for research, diagnostics, and therapeutics. Our tailored immunization campaigns focus on a single animal for optimal results, with sera titer-based selection and PBMC/splenocyte extraction. Precision FACS analysis identifies antigen-positive B cells using a wide range of antigens. Our advanced NGS technology ensures complete VH and VK sequence recovery with full IP ownership. We offer recombinant mAb expression at scales from 100 µg to 1 gram, with multiple backbone options, and robust 3-point ELISA assays for binding, selectivity, and cross-reactivity.