ModDetect™ Panels
ModDetect® panels provide a streamlined way to identify chemical modifications in nucleic acids, regardless of sequence context or modification site.
Specialist reagents for localising and quantifying modified oligonucleotides, mRNA therapeutics and nucleic acid-based medicines.
2BScientific is proud to supply Rockland ModDetect™ Panels to UK researchers, supporting advanced work in oligonucleotide therapeutics, RNA-based drug development, mRNA vaccines and nucleic acid modification analysis.
ModDetect™ Panels are designed to help researchers detect specific chemical modifications in nucleic acids without relying on the sequence or location of the modification. This makes them a powerful tool for laboratories studying modified RNA, DNA, ASOs, siRNA, gapmers, aptamers and other nucleic acid therapeutic formats.
Why choose ModDetect™ Panels?
Developing custom antibodies or specialist reagents for modified nucleic acids can be time-consuming, expensive and technically challenging. ModDetect™ Panels help simplify this process by giving researchers access to pre-developed specialty reagent panels that can be screened against their own candidate molecules.
These panels are especially useful where researchers need to:
- Detect chemically modified oligonucleotides
- Compare reagent performance across candidate therapeutics
- Support assay development for nucleic acid-based drugs
- Study intracellular localisation or biodistribution
- Investigate modified backbones and ribose modifications
- Reduce reliance on custom antibody development
A faster route to assay development
ModDetect™ Panels are designed to save researchers time during candidate evaluation. Instead of beginning with a custom antibody development project, laboratories can screen a panel of reagents and select the best-performing option for their specific oligonucleotide or nucleic acid target.
Each panel includes multiple reagents for testing and selection, with formats available for different immunoassay approaches. The Rockland flyer notes that panels include five reagents for performance screening, three secondary antibodies, and options for unconjugated or biotin-conjugated panels.
Supporting research into oligonucleotide and RNA therapeutics
ModDetect™ Panels can support a wide range of nucleic acid structures and therapeutic platforms, including:
Oligonucleotide formats
- Anti-sense oligonucleotides, including ASOs
- Small interfering RNA, including siRNA
- microRNA, including miRNA
- Aptamers
Nucleic acid configurations
- Single-stranded RNA
- Double-stranded RNA
- DNA-RNA hybrids
- RNA-DNA heterosubstrates and gapmers
Drug discovery platforms
- RNA therapeutic candidates
- DNA and RNA mimic structures
- Modified oligonucleotide drug platforms
Applications for ModDetect™ Panels
ModDetect™ Panels can be used as analytical tools across the drug discovery and development workflow, from early candidate screening through to pre-clinical, clinical and non-clinical studies.
Typical applications include:
Benefits for academic research laboratories
Available from 2BScientific in the UK
2BScientific is currently supporting UK access to Rockland ModDetect™ Panels, making it easier for researchers to source these specialist reagents through a UK-based life science distributor.
Whether your laboratory is working on ASOs, siRNA, mRNA therapeutics, RNA vaccines, gapmers or other nucleic acid-based technologies, our team can help identify the most suitable ModDetect™ Panel for your application.
Enquire about ModDetect™ Panels
Speak to 2BScientific about Rockland ModDetect™ Panels for nucleic acid modification detection, oligonucleotide therapeutic research and RNA-based assay development.
Contact us today to discuss the right ModDetect™ Panel for your research.
