Human Corin ELISA Kit
Product Sizes
1 kit
£738.00
KOA0759-1KIT
About this Product
- SKU:
- KOA0759
- Additional Names:
- activated protease fragment, ATC 2, ATC2, Atrial natriuretic peptide-converting enzyme, Atrial natriuteric peptide converting enzyme, Corin, Corin serine peptidase, CORIN_HUMAN, CRN, Heart specific serine proteinase, Heart specific serine proteinase ATC2, Heart-specific serine proteinase ATC2, Lrp 4, Lrp4, MGC119742, Pro ANP convertase, Pro ANP converting enzyme, Pro-ANP-converting enzyme, TMPRSS 10, TMPRSS10, Transmembrane protease serine 10|CORIN
- Application:
- ELISA
- CE/IVD:
- RUO
- Extra Details:
- Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What's more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension.
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: S67-N1042
- Range:
- 62.5 pg/ml - 4000 pg/ml
- Reactivities:
- Human
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Natural and recombinant human Corin. There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=KOA0759
