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Assay Kits & ELISAs

Human Renin ELISA Kit

Product Sizes
1 kit
£738.00
KOA0735-1KIT
About this Product
SKU:
KOA0735
Additional Names:
ATP6AP2, ATP6M8-9, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H(+)-transporting lysosomal-interacting protein 2, Embryonic liver differentiation factor 10, ER-localized type I transmembrane adaptor, N14F, Renin receptor, Renin/prorenin receptor, RENR_HUMAN, V-ATPase M8.9 subunit, Vacuolar ATP synthase membrane sector-associated protein M8-9|REN
Application:
ELISA
CE/IVD:
RUO
Extra Details:
Renin, also known as an angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system(RAS). This gene is mapped to 1q32.1. Renin's primary function is to cause an increase in blood pressure, leading to restoration of perfusion pressure in the kidneys. It also can catalyze the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release, vasoconstriction. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. What's more, Renin secretion is also stimulated by sympathetic nervous stimulation, mainly through beta-1 adrenoceptor activation.
Immunogen:
Expression system for standard: NSO; Immunogen sequence: L67-R406
Range:
31.2 pg/ml - 2000 pg/ml
Reactivities:
Human
Sensitivity:
<10 pg/ml
Shipping Conditions:
Blue Ice
Specificity:
Natural and recombinant human Renin. There is no detectable cross-reactivity with other relevant proteins.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Assay Kits: ELISAs