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Assay Kits & ELISAs

Mouse TNFRSF9 - 4-1BB ELISA Kit

Product Sizes
1 kit
£738.00
KOA0655-1KIT
About this Product
SKU:
KOA0655
Additional Names:
4-1BB, 4-1BB ligand receptor, CD137, CD137 antigen, CDw137, Homolog of mouse 4 1BB, ILA, Induced by lymphocyte activation (ILA), Interleukin activated receptor homolog of mouse Ly63, Receptor protein 4 1BB, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, TNR9_HUMAN, Tumor necrosis factor receptor superfamily member 9|TNFRSF9
Application:
ELISA
CE/IVD:
RUO
Extra Details:
CD137 is a member of the tumor necrosis factor(TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9(TNFRSF9), 4-1BB and induced by lymphocyte activation(ILA). CD137 gene was localized to chromosome 1p36.Members of this receptor family and their structurally related ligands are important regulators of a wide variety of physiological processes and play an especially important role in the regulation of immune responses. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Immunogen:
Expression system for standard: NSO; Immunogen sequence: V24-L187
Range:
31.2 pg/ml - 2000 pg/ml
Reactivities:
Mouse
Sensitivity:
<10 pg/ml
Shipping Conditions:
Blue Ice
Specificity:
Natural and recombinant mouse TNFRSF9. There is no detectable cross-reactivity with other relevant proteins.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Assay Kits: ELISAs