Human TNFRSF9 - 4-1BB ELISA Kit
Product Sizes
1 kit
£738.00
KOA0616-1KIT
About this Product
- SKU:
- KOA0616
- Additional Names:
- 4-1BB, 4-1BB ligand receptor, CD137, CD137 antigen, CDw137, Homolog of mouse 4 1BB, ILA, Induced by lymphocyte activation (ILA), Interleukin activated receptor homolog of mouse Ly63, Receptor protein 4 1BB, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, TNR9_HUMAN, Tumor necrosis factor receptor superfamily member 9|TNFRSF9
- Application:
- ELISA
- CE/IVD:
- RUO
- Extra Details:
- CD137 is a member of the tumor necrosis factor(TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9(TNFRSF9), 4-1BB and induced by lymphocyte activation(ILA). CD137 gene was localized to chromosome 1p36.Members of this receptor family and their structurally related ligands are important regulators of a wide variety of physiological processes and play an especially important role in the regulation of immune responses. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. The best characterized activity of CD137 is its costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: L24-Q186
- Range:
- 31.2 pg/ml - 2000 pg/ml
- Reactivities:
- Human
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Natural and recombinant human TNFRSF9. There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=KOA0616
