Human TNFRSF18 - GITR ELISA Kit
Product Sizes
1 kit
£738.00
KOA0454-1KIT
About this Product
- SKU:
- KOA0454
- Additional Names:
- Activation inducible TNFR family receptor, AITR, GITR, GITR D, Glucocorticoid induced TNFR related protein, Tumor necrosis factor receptor superfamily member 18|TNFRSF18
- Application:
- ELISA
- CE/IVD:
- RUO
- Extra Details:
- Tumor necrosis factor receptor superfamily member 18(TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. This gene is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: Q26-E161
- Range:
- 62.5 pg/ml - 4000 pg/ml
- Reactivities:
- Human
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Natural and recombinant human TNFRSF18. There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=KOA0454
