Human CXCL10 - IP-10 ELISA Kit
Product Sizes
1 kit
£738.00
KOA0429-1KIT
About this Product
- SKU:
- KOA0429
- Additional Names:
- 10 kDa interferon gamma-induced protein, C7, Chemokine CXC motif ligand 10, Crg 2, CRG2, CXCL10, CXL10_HUMAN, Gamma IP10, gIP 10, GIP10, IFI10, INP 10, Interferon activated gene 10, Interferon gamma induced cell line, Interferon inducible cytokine IP10, IP 10, IP-10, MOB1, SCYB10, Small inducible cytokine B10, Small inducible cytokine B10 precursor, Small inducible cytokine subfamily B (Cys X Cys) member 10, Small inducible cytokine subfamily B CXC member 10, Small-inducible cytokine B10|CXCL10
- Application:
- ELISA
- CE/IVD:
- RUO
- Extra Details:
- Chemokine(C-X-C motif) ligand 10(CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein(gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3.
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: V22-P98
- Range:
- 31.2 pg/ml - 2000 pg/ml
- Reactivities:
- Human
- Sensitivity:
- <1 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Natural and recombinant human CXCL10. There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=KOA0429
