Rat CD80 - B7-1 ELISA Kit
Product Sizes
1 kit
£738.00
KOA0412-1KIT
About this Product
- SKU:
- KOA0412
- Additional Names:
- Activation B7-1 antigen, B7, BB1, CD80, CD80_HUMAN, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD82|CD80
- Application:
- ELISA
- CE/IVD:
- RUO
- Extra Details:
- The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: I39-Q248
- Range:
- 62.5 pg/ml - 4000 pg/ml
- Reactivities:
- Rat
- Sensitivity:
- <2 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Natural and recombinant rat CD80. There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=KOA0412
