Human Cathepsin D ELISA Kit
Product Sizes
1 kit
£742.00
KOA0387-1KIT
About this Product
- SKU:
- KOA0387
- Additional Names:
- CATD_HUMAN, Cathepsin D heavy chain, Ceroid lipofuscinosis neuronal 10, CLN10, CPSD, ctsd, Lysosomal aspartyl protease|CTSD
- Application:
- ELISA
- CE/IVD:
- RUO
- Extra Details:
- Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: L21-L412
- Range:
- 156 pg/ml - 10000 pg/ml
- Reactivities:
- Human
- Sensitivity:
- <10 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Natural and recombinant human Cathepsin D. There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=KOA0387
