Mouse CD30L ELISA Kit
Product Sizes
1 kit
£738.00
KOA0348-1KIT
About this Product
- SKU:
- KOA0348
- Additional Names:
- CD153 antigen, CD30 antigen ligand, CD30 L, CD30 ligand, CD30L, CD30LG, MGC138144, TNFSF8, Tumor necrosis factor (ligand) superfamily member 8, Tumor necrosis factor ligand superfamily member 8|TNFSF8
- Application:
- ELISA
- CE/IVD:
- RUO
- Extra Details:
- The human CD30L(CD153) gene is located at 9q33. It contains 4 exons and spans more than 17.1 kb. CD153 is expressed on the surface of B cells and this expression is upregulated upon CD154(CD40LG), IL4, and B-cell receptor engagement. In these cells, engagement of CD153 by T cell CD30 inhibits immunoglobulin class switch recognition as well as IgG, IgA, and IgE production, suggesting that this "reverse signaling" modulates the CD154-dependent switching of B cells into the pool producing IgG, IgA, and IgE. Additionally, recombinant human CD30L enhanced the proliferation of CD3 -activated T cells, but induced differential responses, including cell death, in several CD30-positive lymphoma-derived cell lines. The standard product used in this kit is recombinant mouse CD30L with the molecular mass of 30-45KDa.
- Immunogen:
- Expression system for standard: NSO; Immunogen sequence: Q68-D239
- Range:
- 15.6 pg/ml - 1000 pg/ml
- Reactivities:
- Mouse
- Sensitivity:
- <6 pg/ml
- Shipping Conditions:
- Blue Ice
- Specificity:
- Natural and recombinant mouse CD30L. There is no detectable cross-reactivity with other relevant proteins.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=KOA0348
