Parkin phospho S378 Antibody
Product Sizes
100 ul
£704.00
609-401-E07-100UL
About this Product
- SKU:
- 609-401-E07
- Additional Names:
- PRKN|rabbit anti-Parkin pS101 Antibody, E3 ubiquitin-protein ligase parkin, Parkin, Parkin RBR E3 ubiquitin-protein ligase, Parkinson juvenile disease protein 2, Parkinson disease protein 2, PRKN, PARK2
- Application:
- Western Blot
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Parkin pS378 Antibody detects Parkin pS378 protein. Parkin is an E3 ligase in the ubiquitin-proteasome system. Hereditary Parkinson's disease is most commonly caused by mutations in the parkin gene and is characterized by the progressive loss of dopaminergic neurons and the presence of Lewy bodies in the substania nigra. Recent evidence suggests that phosphorylation of parkin at Ser378 may have an important regulatory role on its E3 ubiquitin ligase activity. Anti-Parkin pS378 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Apoptosis research.
- Formulation:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Host:
- Rabbit
- Immunogen:
- Anti-Parkin pS378 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-Parkin pS378 antibody is directed against human Parkin protein. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc ag
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=609-401-E07
