Beta Amyloid pyro E11 Antibody
Product Sizes
50 ug
600-401-J13-50UG
About this Product
- SKU:
- 600-401-J13
- Additional Names:
- APP|rabbit anti-Beta Amyloid pyro E11 Antibody, B Beta-amyloid pyro E11, Alzheimer disease amyloid protein, Beta amyloid, A-beta, ABPP, APPI
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 0.75 mg/ml
- Extra Details:
- The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. Beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. Beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease. Anti-beta Amyloid [Pyro Glu11] antibody is ideal for researchers interested Alzheimer's Research, Cell Cycle and Replication, and Neuroscience research.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- beta Amyloid [Pyro Glu11] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N-terminus 11-pyro E start point of human beta Amyloid.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-Beta Amyloid pyro Glu11 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific to the N-terminus 11-pyro E start point. A BLAST analysis was used to suggest cross-reactivity with Human and Primate based on 100% sequence homology. Cross-reactivity with beta Amyloid pyro Glu11 from other sources has not been determined.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-J13
