VTCN1 Antibody
Product Sizes
100 ug
600-401-FX5-100UG
About this Product
- SKU:
- 600-401-FX5
- Additional Names:
- VTCN1|VTCN1 Antibody, B7X, B7H4, B7S1, B7-H4, B7h.5, VCTN1, PRO1291, UNQ659/PRO1291, V-set domain-containing T-cell activation inhibitor 1, Immune costimulatory protein B7-H4
- Application:
- ELISA, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- T cell immunity plays a critical role in host immune surveillance of tumour cell growth and metastatic spread. VTCN1, also known as B7-H4, is a member of the B7 family of immune regulatory molecules. Expressed primarily on the membrane of lymphoid cells, VTCN1 is an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of VTCN1 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumour cells suppress T cell immunity and facilitate tumour progression. VTCN1 may thus be a useful biomarker for the early detection of ovarian cancer.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti- VTCN1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the internal region of human VTCN1.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-VTCN1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with VTCN1 from other sources has not been determined.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-FX5
