SOD1 Antibody
Product Sizes
100 ug
£586.00
600-401-F20-100UG
About this Product
- SKU:
- 600-401-F20
- Additional Names:
- SOD1|Superoxide dismutase1, Superoxide dismutase Cu-Zn, ALS1, IPOA, SOD1, SOD2, SODC, hSod1
- Application:
- ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- SOD1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to human SOD1.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Amphibian, Bovine, Canine, Fish, Hamster, Human, Mouse, Non-human Primate, Other Species, Porcine, Rabbit, Rat, Sheep
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-SOD1 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with SOD1 from Human, Rat, Mouse, Bovine, Monkey, Invertebrate, Coral (Anthozoa), Dog, Hamster, Pig, Rabbit, Sheep, African clawed frog (Xenopus laevis), Mollusk, Mussel (Perna viridis), Fish (O. melastigma) based on 100% homology with the immunizing sequence. Cross-reactivity with SOD
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-F20
