SNCA Antibody
Product Sizes
100 ug
600-401-ER8-100UG
About this Product
- SKU:
- 600-401-ER8
- Additional Names:
- SNCA|SNCA Antibody, PD1, NACP, PARK1, PARK4, Alpha-synuclein, Non-A beta component of AD amyloid
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Alpha-Synuclein (SNCA) is a hallmark of Alzheimer's disease (1,2). It is a cytoplasmic protein that is predominantly expressed in the central nervous system (2). SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to the decreased caspase-3 activation. SNCA may be involved in the regulation of dopamine release and transport and induces fibrillization of microtubule-associated protein tau (3). Defects in SNCA are associated with familial Parkinson's disease (4,5).
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti-SNCA antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the C-terminus of human SNCA.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- Anti-SNCA antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. SNCA antibody is human, mouse and rat reactive. At least three isoforms of SNCA are known to exist.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-ER8
