NALP5 Antibody
Product Sizes
100 ug
£683.00
600-401-CY3-100UG
About this Product
- SKU:
- 600-401-CY3
- Additional Names:
- NALP5 Antibody, MATER, NALP5, PAN11, PYPAF8, CLR19.8, MATER, NACHT, LRR and PYD domains-containing protein 5, Mater protein homolog|NLRP5
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti-NALP5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of human NALP5.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-NALP5 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with NALP5 from other sources has not been determined.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-CY3
