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Antibodies

MettL7A Antibody

Product Sizes
100 ug
£683.00
600-401-CT4-100UG
About this Product
SKU:
600-401-CT4
Additional Names:
METTL7A|MettL7A Antibody, AAM-B, Methyltransferase-like protein 7A, Protein AAM-B
Application:
ELISA, Western Blot
Buffer:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
Formulation:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Host:
Rabbit
Immunogen:
Anti-MettL7A antibody was prepared from whole rabbit serum produced by repeated immunizations with a 12 amino acid synthetic peptide near the C-terminus of human MettL7A.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Human, Mouse
Shipping Conditions:
Dry Ice
Specificity:
Anti-MettL7A Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of MettL7A are known to exist. This MettL7A antibody is predicted to not cross-react with MettL7B.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody