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Antibodies

EDA1 Antibody

Product Sizes
100 ug
600-401-AZ0-100UG
About this Product
SKU:
600-401-AZ0
Additional Names:
Ectodysplasin A, Ectodermal dysplasia protein, ED1, ED1-A1, ED1-A2, EDA1, EDA2, EDA protein, HED, ODT1, STHAGX1, XHED, XLHED|EDA
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Ectodysplasin A (EDA1) is a member of the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation (1). It is a trimeric type II membrane protein that co-localizes with cytoskeletal structures at the lateral and apical surfaces of cells and can be expressed as eight alternatively spliced isoforms in hair follicles and in the epidermis of adult skin (2,3). EDAs are required during development, and loss or mutation of EDA1 results in a group of developmental disorders identified as ectodermal dysplasia type 1 (4,5).
Formulation:
0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Host:
Rabbit
Immunogen:
Anti-EDA1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 19 amino acid peptide near the internal region of human EDA1.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Dry Ice
Specificity:
Anti-EDA1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. EDA1 antibody is human, mouse and rat reactive. Multiple isoforms of EDA1 are known to exist.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody