CRTC2 Antibody
Product Sizes
100 ug
600-401-AN9-100UG
About this Product
- SKU:
- 600-401-AN9
- Additional Names:
- CRTC2|CRTC2 Antibody, TORC2, TORC-2, TORC2, CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- CRTC2, also known as TORC2 (Transducers Of Regulated cAMP Response Element-Binding (CREB)) 2 and the related protein CRTC1 are potent CREB coactivators that are exported from the nucleus in a CRM1-dependent manner via phosphorylation-dependent interactions. Studies suggest that their phosphorylation and nuclear/cytoplasmic shuttling play an important role in the regulation of gluconeogenesis by cAMP. CRTC2 is present in both B and T-lymphocytes and abundantly expressed in the thymus. Its activity is important in regulating the expression of genes involved in cellular energy metabolism while CRTC1 is essential for energy balance and fertility.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Rabbit
- Immunogen:
- Anti-CRTC2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the C-terminus of human CRTC2.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-CRTC2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of CRTC2 are known to exist. CRTC2 antibody is predicted to not cross-react with CRTC1.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=600-401-AN9