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Antibodies

Beta TrCP2 Antibody

Product Sizes
100 ug
600-401-483-100UG
About this Product
SKU:
600-401-483
Additional Names:
FBXW11|rabbit anti-beta TrCP2 antibody, rabbit anti-BTRCP2 antibody, F-box/WD repeat-containing protein 11, beta Transducin Repeat Containing Protein 2 antibody, BTRC2 antibody, F-box and WD-40 Domain Protein 1B antibody, F-box Protein FBW1B antibody, FBW1B antibody, FBXW1B antibody, Homologous to Slimb protein, HOS, FBXW11
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
0.8 mg/ml
Extra Details:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Rabbit
Immunogen:
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the N-terminal of human B BetaTrCP2 protein.
Isotype:
IgG
Physical State:
Liquid
Reactivities:
Human, Mouse
Shipping Conditions:
Dry Ice
Specificity:
This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human B BetaTrCP2 protein. A BLAST analysis was used to suggest cross-reactivity with B BetaTrCP2 from human, mouse, dog, bovine, chimpanzee, chicken and horse based on a 100% homology with the immunizing sequence. Cross-reactivity with B BetaTrCP2 from other sources has not b
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody
Western blot using Rockland's affinity purified anti-bTrCP2 antibody shows detection of mouse and human bTrCP2 (arrowhead) in NIH3T3 (p/n W10-000-358) [lane 1] and 293 (p/n W09-000-365) [lane 2] whole cell lysates, respectively. The band appears as a 58 kDa protein, although a 62.1 kDa band is predicted. The identity of faint higher molecular weight bands is not known. The primary antibody was used at a 1:200 dilution incubated in 5% BLOTTO overnight at 4°C. Detection occurred using HRP conjugated Goat-anti-Rabbit IgG (p/n 611-103-122) diluted 1:20,000 in blocking buffer (p/n MB-070) for 1 h at 4 °C.