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Antibodies

Alpha Synuclein Antibody

Product Sizes
100 ul
£704.00
500-301-E56-100UL
About this Product
SKU:
500-301-E56
Additional Names:
mouse anti-Alpha Synuclein Antibody, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP|SNCA
Application:
Detection/Quantitation, ELISA, Immunofluorescence, Western Blot
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
translate.label.attr.clone:
2A7
Clonality:
Monoclonal
Extra Details:
Alpha Synuclein Antibody detects Alpha Synuclein protein. Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson's disease (PD) and other neurodegenerative disorders. Early onset Parkinson's disease may be caused by a duplication or triplication of one of the alpha synuclein genes. Alpha-synuclein is also found in the Lewy bodies of patients with diffuse Lewy body disease and inclusions in glial cells in the brains of patients with multiple system atrophy (MSA) and amyotrophic lateral sclerosis (ALS). Anti-Alpha-synuclein antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Mouse
Immunogen:
Anti-Alpha Synuclein Antibody was produced by repeated immunizations with full length human alpha synuclein expressed in E. coli.
Isotype:
IgG, IgG1
Physical State:
Liquid
Reactivities:
Bovine, Human, Mouse, Porcine, Rat
Shipping Conditions:
Dry Ice
Specificity:
Anti-Alpha Synuclein Antibody is directed against human Alpha Synuclein protein. The antibody was purified by protein G purification from tissue culture supernatant. Reactivity is expected against alpha synuclein from most mammalian species based on 100% sequence homology. Cross reactivity with Alpha Synuclein from other sources has not been determined.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Antibody: Monoclonal Antibody