Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

DUX4 Antibody

Product Sizes
100 ug
209-301-F23-100UG
About this Product
SKU:
209-301-F23
Additional Names:
DUX4|mouse anti-DUX4 Antibody, Double homeobox protein 4, Double homeobox protein 10, DUX4, DUX10
Application:
Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
translate.label.attr.clone:
P2B1
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Mouse
Immunogen:
DUX4 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to the C-terminal region of human DUX4 protein.
Isotype:
IgG1
Physical State:
Liquid
Reactivities:
Human
Shipping Conditions:
Dry Ice
Specificity:
Anti-DUX4 Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for human DUX4 protein. A BLAST analysis was used to suggest cross-reactivity with DUX4 from human based on 100% homology with the immunizing sequence. It does not cross react with DUX4c. Cross-reactivity with DUX4 from other sources has not been determined. Transcription Factor research.
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Monoclonal Antibody