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Antibodies

CRP Antibody

Product Sizes
100 ug
209-1132-0100-100UG
About this Product
SKU:
209-1132-0100
Additional Names:
CRP|goat anti-CRP Antibody, C reactive protein pentraxin related antibody, CRP antibody, MGC88244 antibody, PTX 1 antibody, PTX1 antibody
Application:
Dot Blot, ELISA, Immunohistochemistry, Western Blot
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
CRP (C-Reactive Protein) belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. CRP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Diseases associated with CRP include Acute Pancreatitis and Appendicitis. Anti-CRP Antibody is ideal for researchers interested in cAMP Dependent PKA, IL6 signaling, calcium ion binding, and cholesterol binding.
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Goat
Immunogen:
Capsular Reactive Protein (CRP) [Human Serum]
Isotype:
IgG
Physical State:
Lyophilized
Reactivities:
Human
Shipping Conditions:
Ambient
Specificity:
This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Capsular Reactive Pr
Storage Conditions:
2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody
Western Blot Results of Goat Anti-Human CRP Antibody. Lane 1: Rec Human C Reactive Protein - Reduced [0.02ug]. Lane 2: Opal Prestained Molecular Weight Marker (p/n MB-210-0500). Lane 3: Rec Human C Reactive Protein - Non-Reduced [0.02ug]. Primary Antibody: Goat Anti-Hu CRP Antibody at 1:1000 overnight at 2-8°C. Secondary Antibody: Rabbit Anti-Goat IgG HRP (p/n 605-4302) at 1:40,000 for 30 mins at RT. Blocking: Universal BlockOut Buffer (p/n MB-073) for 1hr at RT. Predicted MW: ~24kDa.