Glial Fibrillary Acidic Protein (GFAP) Antibody
Product Sizes
100 ul
£627.00
200-901-D60-100UL
About this Product
- SKU:
- 200-901-D60
- Additional Names:
- GFAP|gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, cb345. Glial fibrillary acidic protein, GFAP antibody, neuroscience antibodies
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- GFAP Antibody detects GFAP. Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers. Therefore, GFAP antibody is ideal for investigators involved in neuropathologic diseases and more generally in Neuroscience.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Chicken/Avian
- Immunogen:
- Anti-GFAP Antibody was produced by repeated immunizations with recombinant and extensively purified bovine GFAP.
- Isotype:
- IgY
- Physical State:
- Liquid
- Reactivities:
- Rat
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-GFAP Antibody is directed against bovine GFAP. The antibody is a total IgY fraction. Expect reactivity with the following species based on sequence homology: human, mouse, rat. Cross reactivity with GFAP from other species has not been determined.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=200-901-D60
