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Antibodies

CD8a Phycoerythrin Antibody

Product Sizes
200 ug
£278.00
200-508-N77-200UG
About this Product
SKU:
200-508-N77
Additional Names:
Cd8a|T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2
Application:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Buffer:
0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
translate.label.attr.clone:
53-6.7
Clonality:
Monoclonal
Conjugate:
R-PE
Extra Details:
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked A Alpha and B Beta chains that form the A Alpha(CD8a)/B Beta(CD8b) heterodimer and A Alpha/A Alpha homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 A Alpha/B Beta heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR A Alpha/B Beta T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 A Alpha/A Alpha homodimer is expressed on a subset of G Gamma/D Delta TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Formulation:
0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Rat
Immunogen:
Anti-CD8a Antibody (Monoclonal) was produced by repeated immunizations with Mouse thymus or spleen .
Isotype:
IgG2a, IgG2a, kappa
Physical State:
Liquid
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
Phycoerythrin conjugated CD8a Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD8a. Cross reactivity with CD8a from other sources has not been tested. Anti-CD8a is conjugated with PE under optimal conditions and the solution is free of unconjugated PE.
Storage Conditions:
2-8[o]C unopened. Protect from light.
Supplier:
Rockland Inc
Type:
Antibody: Monoclonal Antibody
FluoroFinder: