TLR4 Antibody
Product Sizes
100 ug
£624.00
200-501-I26-100UG
About this Product
- SKU:
- 200-501-I26
- Additional Names:
- hToll, Toll-like receptor 4, CD284|Tlr4
- Application:
- Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MTS510
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Anti-TLR4 CD284 Antibody detects human TLR4. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Among this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling. The TLR4 cDNA codes for a protein consisting of 799 amino acids with approximate molecular weight of 88 kDa. Anti-TLR4 CD284 Antibody is ideal for investigators involved in cytokines and growth factor research.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Rat
- Immunogen:
- TLR4 Antibody was produced in rats prepared by repeated immunizations with the Ba/F3 cell line expressing mouse protein TLR4.
- Isotype:
- IgG2a
- Physical State:
- Liquid
- Reactivities:
- Mouse
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-TLR4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR4 from mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR4 from other sources has not been determined. Toll Like Receptors and signaling research.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=200-501-I26
