NK1.1 Allophycocyanin Antibody
Product Sizes
100 ug
£391.00
200-326-N93-100UG
About this Product
- SKU:
- 200-326-N93
- Additional Names:
- Killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, Lymphocyte antigen 55c, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C, Natural killer cell surface protein P1-40, NKR-P1 40, CD161c, Klrb1c, Ly55c, Nkrp1c|Klrb1c
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- translate.label.attr.clone:
- PK136
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 0.2 mg/ml
- Extra Details:
- The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1. The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1.
- Formulation:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Mouse
- Immunogen:
- Anti-NK1.1 Antibody (Monoclonal) was produced by repeated immunizations with NK1.1 antigen.
- Isotype:
- IgG2a, IgG2a, kappa
- Physical State:
- Liquid
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Allophycocyanin conjugated NK1.1 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse NK1.1. Cross reactivity with NK1.1 from other sources has not been tested. Anti-NK1.1 is conjugated with APC under optimal conditions and the solution is free of unconjugated APC.
- Storage Conditions:
- 2-8[o]C unopened. Protect from light.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Monoclonal Antibody
- FluoroFinder:
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=200-326-N93
