CD8 APC Antibody
Product Sizes
500 ul
200-326-M64-500UL
About this Product
- SKU:
- 200-326-M64
- Additional Names:
- CD8A|T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
- Application:
- Flow Cytometry
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- translate.label.attr.clone:
- RPA-T8
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Concentration:
- 0.05 mg/ml
- Extra Details:
- CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.
- Formulation:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Mouse
- Immunogen:
- Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
- Isotype:
- IgG1, IgG1, kappa
- Physical State:
- Liquid
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Allophycocyanin conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8. Reactivity is observed against human CD8, chimpanzee, baboon, cynomolgus, rhesus, and ooty mangabey. Cross reactivity with CD8 from other sources has not been tested.
- Storage Conditions:
- 2-8[o]C unopened. Protect from light.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=200-326-M64
