CD8 Fluorescein Antibody
Product Sizes
500 ul
£175.00
200-302-M64-500UL
About this Product
- SKU:
- 200-302-M64
- Additional Names:
- CD8A|T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
- Application:
- Flow Cytometry
- Buffer:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- translate.label.attr.clone:
- RPA-T8
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Concentration:
- 0.2 mg/ml
- Extra Details:
- CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.
- Formulation:
- 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Host:
- Mouse
- Immunogen:
- Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
- Isotype:
- IgG1, IgG1, kappa
- Physical State:
- Liquid
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Fluorescein conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8. Reactivity is observed against human CD8 and chimpanzee. Cross reactivity with CD8 from other sources has not been tested.
- Storage Conditions:
- 2-8[o]C diluted. Do not freeze. Protect from light.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Monoclonal Antibody
- FluoroFinder:
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=200-302-M64
