PD-1 Antibody [7A11B1]
Product Sizes
100 ug
£711.00
200-301-DK3-100UG
About this Product
- SKU:
- 200-301-DK3
- Additional Names:
- PD-1 Antibody [7A11B1] , PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1|PDCD1
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride
- CE/IVD:
- RUO
- translate.label.attr.clone:
- 7A11B1
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
- Formulation:
- 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Host:
- Mouse
- Immunogen:
- Anti-PD-1 antibody was produced in mice by repeated immunizations with a ~150 amino acid recombinant protein from near the N-terminus of mouse PD-1.
- Isotype:
- IgG1
- Physical State:
- Liquid
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- Anti-PD-1 Monoclonal Antibody was Protein A purified. Cross reactivity with PD-1 [7A11B1] from other sources has not been determined.
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Rockland Inc
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=200-301-DK3
