IKB alpha C-terminal Peptide
Product Sizes
50 ug
£222.00
100-4167CP-50UG
About this Product
- SKU:
- 100-4167CP
- Additional Names:
- NF-kappa-B inhibitor alpha peptide, I-kappa-B-alpha antibody, IkB-alpha, IkappaBalpha, IKBA, MAD3, NFKBI, control peptide, blocking peptide
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Concentration:
- 1 mg/ml
- Extra Details:
- Intended for use as a control peptide when used with anti-IKB alpha C-terminal specific to block specific interaction of anti-IKB alpha C-terminal specific [p/n 100-4167C] with the IKB alpha subunit. I-kappa-B-alpha inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, IKBA becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Physical State:
- Liquid
- Purity:
- >95%
- Shipping Conditions:
- Dry Ice
- Specificity:
- Greater than 95% specific peptide
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=100-4167CP
