NFKB p65 (Rel A) Peptide
Product Sizes
50 ug
£222.00
100-4165P-50UG
About this Product
- SKU:
- 100-4165P
- Additional Names:
- NFKB p65 peptide, Rel A peptide, Transcription factor p65, control peptide, blocking peptide|RELA
- Buffer:
- None
- CE/IVD:
- RUO
- Concentration:
- 1 mg/ml
- Extra Details:
- NFKB p65 which is a component of NFKB. NFKB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFkappaB bound to IkappaB. NFkappaB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFKB1) subunits. Other identified subunits include p52 (NFKB2), c-Rel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFkappaB subunit p65, similar to p50/p65 heterodimers. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by IkappaB alpha. IkappaB alpha binds to the p65 subunit, preventing nuclear localization and DNA binding. Low levels of p52 and p50 homodimers can also exist in cells.
- Immunogen:
- RELA
- Physical State:
- Liquid
- Purity:
- >95%
- Shipping Conditions:
- Dry Ice
- Specificity:
- Greater than 95% specific peptide
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=100-4165P
