Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Carbonic Anhydrase II Antibody

Product Sizes
2 ml
£1343.00
100-4157-2ML
About this Product
SKU:
100-4157
Additional Names:
CA2|rabbit anti-Carbonic Anhydrase II Antibody, Carbonate dehydratase II antibody, Carbonic anhydrase 2 antibody, Carbonic anhydrase B antibody, Carbonic anhydrase C antibody, Carbonic anhydrase II antibody, Carbonic dehydratase antibody
Application:
ELISA, Immunofluorescence, Western Blot
Buffer:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
CE/IVD:
RUO
Clonality:
Polyclonal
Concentration:
85 mg/ml
Extra Details:
Carbonic Anhydrase 2 is essential for bone resorption and osteoclast differentiation. It reverses hydration of carbon dioxide and can hydrate cyanamide to urea. It is involved in the regulation of fluid secretion into the anterior chamber of the eye. Carbonic Anhydrase II contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. It stimulates the chloride-bicarbonate exchange activity of SLC26A6. it is used for target of drugs used in treatments against glaucoma disorder and breast cancer.
Format:
Antiserum
Formulation:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Host:
Rabbit
Immunogen:
Carbonic Anhydrase II [Bovine Erythrocytes]
Physical State:
Lyophilized
Reactivities:
Bovine
Shipping Conditions:
Ambient
Specificity:
This product was prepared from monospecific antiserum by a delipidation and defibrination. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-rabbit serum, purified and partially purified Carbonic Anhydrase II [Bovine Erythrocytes]. Cross reactivity against Carbonic Anhydrase II from other tissues and species may occur but have not been specifically determined.
Storage Conditions:
2-8[o]C liquid. Aliquot. Avoid freeze/thaw cycles., -20[o]C/-70[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Polyclonal Antibody
The correlative workflow combining immuno-fluorescence microscopy and immuno-electron microscopy with NanoSIMS imaging using Anti-Carbonic Anhydrase II Antibody. The cryo section (ca. 100 nm thick) was imaged after simultaneous immunolocalization of carbonic anhydrase with anti-Alexa-associated secondary antibodies (a and b) and B Beta-tubulin observed in TEM by 10 nm gold particles associated to the secondary antibody (c and d). The fluorescence microscope images (a and b; zoom in a) and the TEM micrographs (c and d; zoom in c) exhibit identical areas of the same thin section. e and f are NanoSIMS images showing the 13C and 15N distributions in the interior of a dinoflagellate symbiont. The area imaged is indicated by a red square in c. Scale bars: a and c: 5 um; b and d: 500 nm; e and f: 2 um. Fig 4. PMID: 32647198.