Llama IgG2 isotype control
Product Sizes
0.5 mg
£273.00
025-0144-0.5MG
About this Product
- SKU:
- 025-0144
- Additional Names:
- Llama IgG2 isotype, Llama IgG2 subclass isotype, Llama IgG2a, IgG2b, IgG2c
- Application:
- ELISA, Flow Cytometry, SDS-PAGE, Western Blot
- Buffer:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Concentration:
- 1.2 mg/ml
- Extra Details:
- Comparative studies of old world camelids (Camelus bactrianus and Camelus dromedarius) and new world camelids (Lama pacos, Lama glama and Lama vicugna) have shown that heavy-chain-only immunoglobulins represent between 35% - 70% of total IgG in the sera of all species. Such antibodies are homodimers of heavy chains that lack the CH1 domain of conventional antibodies and therefore do not interact with light chains, exhibiting a lower molecular weight ~100 kDa. In llama and other species of camelids, these heavy-chain-only immunoglobulins belong to the IgG2 and IgG3 subclasses of gamma chain antibodies.
- Formulation:
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Isotype:
- IgG
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Llama IgG2 isotype control (which consists of IgG2a, IgG2b and IgG2c isotypes) has been prepared from llama serum by multiple chromatography steps using a combination of protein A and protein G chromatography. Coomassie stained SDS-PAGE of non-reduced llama IgG2 shows a band of ~100 kDa whereas the reduced form exhibits ~46 kDa. No bands corresponding to llama IgG1 or IgG3 are observed.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Isotype Controls
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=025-0144
