Llama IgG1 isotype control
Product Sizes
0.5 mg
£273.00
025-0140-0.5MG
About this Product
- SKU:
- 025-0140
- Additional Names:
- Llama IgG1 isotype, Llama IgG1 subclass isotype
- Application:
- ELISA, Flow Cytometry, Immunofluorescence, SDS-PAGE, Western Blot
- Buffer:
- See application note.
- CE/IVD:
- RUO
- Concentration:
- 1 mg/ml
- Extra Details:
- Comparative studies of old world camelids (Camelus bactrianus and Camelus dromedarius) and new world camelids (Lama pacos, Lama glama and Lama vicugna) have shown that heavy-chain-only immunoglobulins represent between 35% - 70% of total IgG in the sera of all species. Such antibodies are homodimers of heavy chains that lack the CH1 domain of conventional antibodies and therefore do not interact with light chains, exhibiting a lower molecular weight ~100 kDa. In llama and other species of camelids, these heavy-chain-only immunoglobulins belong to the IgG2 and IgG3 subclasses. All gamma chain camelid antibodies exhibiting the more conventional assembly of two light and two heavy chains with molecular weight ~150 kDa, belong to the IgG1 subclass.
- Isotype:
- IgG1
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Specificity:
- Llama IgG1 isotype control has been prepared from llama serum by multiple chromatography steps using a combination of protein A and protein G chromatography. Coomassie stained SDS-PAGE of non-reduced llama IgG1 shows a band of ~150 kDa whereas the reduced form exhibits ~55 kDa (heavy chain) and ~25 kDa (light chain). No bands corresponding to llama IgG2 or IgG3 are observed.
- Storage Conditions:
- -20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Rockland Inc
- Type:
- Antibody: Isotype Controls
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=025-0140
