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Antibodies

Llama IgG Whole Molecule

Product Sizes
0.5 mg
£270.00
025-0102-0.5MG
About this Product
SKU:
025-0102
Additional Names:
Immunoglobulin G from Llama, IgG from Llama, Llama IgG, Llama IgG Whole Molecule
Application:
ELISA, Flow Cytometry, SDS-PAGE, Western Blot
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
1.40 mg/ml
Extra Details:
Comparative studies of old world camelids (Camelus bactrianus and Camelus dromedarius) and new world camelids (Lama pacos, Lama glama and Lama vicugna) have shown that heavy-chain-only immunoglobulins represent between 35% - 70% of total IgG in the sera of all species. Such antibodies are homodimers of heavy chains that lack the CH1 domain of conventional antibodies and therefore do not interact with light chains, exhibiting a lower molecular weight ~100 kDa. In llama and all other species of camelids, these heavy-chain-only immunoglobulins belong to the IgG2 and IgG3 subclasses of gamma chain antibodies. All gamma chain camelid antibodies exhibiting the more conventional assembly of two light and two heavy chains with molecular weight ~150 kDa, belong to the IgG1 subclass.
Isotype:
IgG
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Specificity:
Llama IgG has been prepared from llama serum by multiple chromatography steps using a combination of protein A and protein G chromatography. This product contains equal amounts of IgG1, IgG2 and IgG3. Coomassie stained SDS-PAGE of non-reduced llama IgG1 shows a band of ~150 kDa whereas the reduced form exhibits ~55 kDa (heavy chain) and ~25 kDa (light chain); non-reduced llama IgG2 shows a band of
Storage Conditions:
-20[o]C aliquoted. Aliquot. Avoid freeze/thaw cycles., 2-8[o]C diluted. Aliquot. Avoid freeze/thaw cycles.
Supplier:
Rockland Inc
Type:
Antibody: Isotype Controls