rRat IL-1 beta Protein
Product Sizes
100 ug
£1049.00
012-001-301-0100-100UG
About this Product
- SKU:
- 012-001-301-0100
- Additional Names:
- Catabolin, LAF, EP, LEM, MCF|Il1b
- Application:
- Cell-based/Functional Assay, SDS-PAGE
- Buffer:
- 0.01 M Sodium Phosphate
- CE/IVD:
- RUO
- Extra Details:
- Interleukin-1 beta (IL-1B Beta) is a pro-inflammatory cytokine, produced in response to inflammatory agents by a variety of cells, including, monocytes, macrophages, and dendritic cells (DCs). IL-1B Beta and IL-1A Alpha are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1A Alpha is cell associated and IL-1B Beta is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant rat IL-1B Beta is a non-glycosylated protein, containing 152 amino acids, with a molecular weight of 17.3 kDa.
- Formulation:
- 0.01 M Sodium Phosphate, pH 7.5
- Immunogen:
- Il1b
- Physical State:
- Lyophilized
- Purity:
- >97%
- Shipping Conditions:
- Ambient
- Specificity:
- Interleukin-1 beta purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=012-001-301-0100
