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Proteins and Peptides

rMouse SDF-1 Beta/CXCL12 Protein

Product Sizes
10 ug
010-001-W23-0010-10UG
About this Product
SKU:
010-001-W23-0010
Additional Names:
12-O-tetradecanoylphorbol 13-acetate repressed protein 1 (TPAR1), C-X-C motif chemokine 12, Pre-B cell growth-stimulating factor (PBSF), Thymic lymphoma cell-stimulating factor (TLSF)|Cxcl12
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Extra Details:
Stromal Derived Growth Factor-1B Beta (SDF-1B Beta), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1B Beta signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human SDF-1B Beta shares 100% identity to feline SDF-1B Beta. Recombinant mouse SDF-1B Beta is a non-glycosylated protein, containing 72 amino acids, with a molecular weight of 8.5 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
Cxcl12
Physical State:
Lyophilized
Purity:
>97%
Shipping Conditions:
Ambient
Specificity:
Stromal Cell-Derived Factor-1 beta (CXCL12) purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Mouse Stromal Cell-Derived Factor-1 beta (CXCL12) Recombinant Protein. Lane 1: 1 ug Mouse SDF-1 beta in reducing conditions (+). Lane 2: 1 ug Mouse SDF-1 beta in non-reducing conditions (-). Lane 3: Molecular weight marker. Mouse SDF-1 beta is predicted to be a 8.5 kDa.
Bioactivity of Mouse Stromal Cell-Derived Factor-1 beta (CXCL12) Recombinant Protein. Human T cells were allowed to migrate to Mouse SDF-1B Beta at (0, 5, 20, 100, 500 ng/mL). After 4 hours, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above. Significant increases in migration over basal levels were seen in response to Mouse SDF-1B Beta detectable starting at between 5-100 ng/mL.