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Proteins and Peptides

rMouse M-CSF Protein

Product Sizes
10 ug
£319.00
010-001-V78-0010-10UG
About this Product
SKU:
010-001-V78-0010
Additional Names:
Csf1|MGI-IM
Application:
Cell-based/Functional Assay
Buffer:
See application note.
CE/IVD:
RUO
Concentration:
0.1 mg/ml
Extra Details:
Macrophage Colony Stimulating Factor (M-CSF) is hematopoietic growth factor produced by a wide variety of cells. M-CSF is known to stimulate differentiation of hematopoietic stem cells to monocyte-macrophage cell populations in culture. M-CSF acts through the CSF receptor 1. Although human M-CSF shows activity on mouse cells, mouse CSF shows no activity on human cells. Recombinant mouse M-CSF is a disulfide-linked homodimer, containing two 156 amino acid chains, with a total molecular weight of 36.8 kDa.
Immunogen:
Csf1
Physical State:
Lyophilized
Purity:
>98%
Shipping Conditions:
Ambient
Specificity:
Macrophage Colony Stimulating Factor purity was determined to be greater than 98% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Bioactivity of Mouse Macrophage Colony Stimulating Factor Recombinant Protein. Serial dilutions of Mouse M-CSF, starting at 50 ng/mL, were added to NSF-60 cells. Cell proliferation was measured after 44 hours and the linear portion of the curve was us used to calculate the ED50. The ED50 of Mouse M-CSF is 1.1-1.6 ng/mL. This value is comparable with the typical expected range of < 2 ng/mL.