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Proteins and Peptides

rMouse IL-16 Protein

Product Sizes
10 ug
£319.00
010-001-V55-0010-10UG
About this Product
SKU:
010-001-V55-0010
Additional Names:
Il16|Lymphocyte Chemoattractant Factor (LCF)
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.01 M Sodium Phosphate
CE/IVD:
RUO
Concentration:
0.1 mg/ml
Extra Details:
Interleukin 16 (IL-16) is produced primarily by CD4+ and CD8+ T cells and acts as a chemo-attractant for lymphocytes, monocytes, eosinophils, dendritic cells and Langerhans cells. Additionally, IL-16 has been reported to upregulate IL-2 receptor (CD25), induce progression of cells to the G1 phase and suppress HIV & SIV replication. Recombinant mouse IL-16 is a non-glycosylated protein, containing 127 amino acids, with a molecular weight of 13.2 kDa.
Formulation:
0.01 M Sodium Phosphate, pH 7.5
Immunogen:
Il16
Physical State:
Lyophilized
Purity:
>95%
Shipping Conditions:
Ambient
Specificity:
Interleukin-16 purity was determined to be greater than 95% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Mouse Interleukin-16 Recombinant Protein. Lane 1: 1 ug Mouse IL-16 in non-reducing conditions (-). Lane 2: 1 ug Mouse IL-16 in reducing conditions (+). Lane 3: Molecular weight marker. Mouse IL-16 has a predicted MW of 13.2 kDa.
Bioactivity of Mouse Interleukin-16 Recombinant Protein. Human T cells were allowed to migrate to Mouse IL-16 at (0, 5, 20, 100 and 500 ng/mL). After 4 hours, cells that migrated were counted using a luminescent substrate and displayed on the bar graph above. Significant increases in migration over basal levels were seen in response to Mouse IL-16 starting at 5 ng/mL.