Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

rMouse IGF-I Protein

Product Sizes
10 ug
£184.00
010-001-V21-0010-10UG
About this Product
SKU:
010-001-V21-0010
Additional Names:
Igf1|Somatamedin C, mechano growth factor, IGF-IA
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.1% Trifluoroacetic acid
CE/IVD:
RUO
Concentration:
0.1 mg/ml
Extra Details:
Insulin-like Growth Factor I, IGF-I, is a growth factor produced in response to growth hormone-stimulated liver and can be found circulating throughout the body and throughout life. IGF-I activates the IGF-I receptor (IGF1R) and the insulin receptor to mediate growth of almost every cell of the body. IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. Mature human IGF-I is 100% homologous with bovine and porcine proteins. Recombinant mouse IGF-I is a non-glycosylated protein, containing 70 amino acids, with a molecular weight of 7.6 kDa.
Formulation:
0.1% Trifluoroacetic acid
Immunogen:
Igf1
Physical State:
Lyophilized
Purity:
>98%
Shipping Conditions:
Ambient
Specificity:
Insulin-like Growth Factor I purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Mouse Insulin-like Growth Factor I Recombinant Protein. Lane 1: Molecular weight marker. Lane 2: 1 ug Mouse IGF-I in non-reducing conditions (-). Lane 3: Molecular weight marker. Lane 4: 1 ug Mouse IGF-I AF in reducing conditions (+). Mouse IGF-I has a predicted MW of 7.6 kDa.
Bioactivity of Mouse Insulin-like Growth Factor I Recombinant Protein. FDC-P1 cells were cultured with 0 to 250 ng/mL Mouse IGF-I. Cell proliferation was measured after 48 hours and the linear portion of the curve was us used to calculate the ED50. The ED50 of Mouse IGF-I is 14-21 ng/mL. This value is comparable to the competitor sample.