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Proteins and Peptides

rMouse G-CSF Protein

Product Sizes
100 ug
£919.00
010-001-U93-0100-100UG
About this Product
SKU:
010-001-U93-0100
Additional Names:
CSF-3, MGI-1G, GM-CSFB Beta, pluripoietin|Csf3
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
0.01 M Sodium Citrate
CE/IVD:
RUO
Extra Details:
Granulocyte Colony-Stimulating Factor, or G-CSF, is a growth factor that is considered the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, IL-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF, while in epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by IL-17. Human and mouse G-CSF are cross-reactive. Recombinant mouse G-CSF is a non-glycosylated protein, containing 179 amino acids, with a molecular weight of 19 kDa.
Formulation:
0.01 M Sodium Citrate, pH 3.0
Immunogen:
Csf3
Physical State:
Lyophilized
Purity:
>98%
Shipping Conditions:
Ambient
Specificity:
Granulocyte Colony Stimulating Factor purity was determined to be greater than 98% as determined by analysis by UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
SDS-PAGE of Mouse Granulocyte Colony Stimulating Factor Recombinant Protein. Lane 1: 1 ug Mouse G-CSF in reducing conditions (+). Lane 2: Molecular weight marker. Mouse G-CSF has a predicted MW of 19 kDa.
Bioactivity of Mouse Granulocyte Colony Stimulating Factor Recombinant Protein. Serial dilutions of Mouse G-CSF, starting at 10 ng/mL, were added to NFS-60 cells. After 69 hours, cell proliferation was measured and the linear portion of the curve was us used to calculate the ED50. The ED50 of Murine G-CSF is 8-12 pg/mL. This value is comparable with the typical expected range of 10-60 pg/mL.